Gram Negative Coccobacilli
An 18-month-old baby girl is suspected to have Haemophilus influenzae meningitis. She has not been immunized with the HIB vaccine. A rapid latex agglutination test is performed with the spinal fluid to make a definitive diagnosis. What chemical component in the spinal fluid are we detecting with this assay? (AIPG 2010)
a. The latex agglutination test involves the use of latex beads coated with specific antibody that become agglutinated in the presence of homologous bacteria or antigen.
b. This test is used to determine the presence of the capsular polysaccharide antigen of Haemophilus influenzae in serum or spinal fluid.