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Pathology

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Neoplasia

Question
5 out of 24
 

An example of a tumour suppressor gene is: (AIPG 2011)



A Myc.
B Fos
C Ras
D Rb

Ans. D Rb

a. Tumor suppressor gene regulate the cell growth. Protein product of these gene apply brakes to cell proliferation. They are recessive cancer gene.

b. Tumor associated with Rb gene mutation - Retinoblastoma Q; Osteosarcoma Q; Glioblastoma; Carcinoma breast, colon, lung, bladder.

c. Myc, Fos, and ras are oncogene (dominant cancer gene).

Neoplasia Flashcard List

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