An example of a tumour suppressor gene is: (AIPG 2011)
a. Tumor suppressor gene regulate the cell growth. Protein product of these gene apply brakes to cell proliferation. They are recessive cancer gene.
b. Tumor associated with Rb gene mutation - Retinoblastoma Q; Osteosarcoma Q; Glioblastoma; Carcinoma breast, colon, lung, bladder.
c. Myc, Fos, and ras are oncogene (dominant cancer gene).