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Microbiology

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Gram Negative Coccobacilli

Question
36 out of 58
 

An inhibitor was designed to block a biologic function in H. influenzae. If the goal of the experiment was to reduce the virulence of H. influenzae, the most likely target would be which of the following?



A Capsule formation
B Endotoxin assembly

C Exotoxin liberator
D Flagella synthesis

Ans. A Capsule formation

a. The major determinant of virulence in H. influenzae is the presence of a capsule. There is no demonstrable exotoxin, and the role of endotoxin is unclear.

b. While one would expect that IgA protease would inhibit local immunity, the role of this enzyme in pathogenesis is as yet unclear.

Gram Negative Coccobacilli Flashcard List

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