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Tumor Calcinosis

Periarticular extra capsular soft tissue masses of hyroxyapatite or amorphous calcium phosphate complex around major joints most often shoulder, hip & ankle is seen in tumor calcinosis. Disease usually appears in childhood & grows life-long.

The primary defect is hyper phosphatemia resulting from increase reabsorption of filtered phosphate by renal tubules. The most common findings are hyper phosphatemia, & elevated 1,25- dihydroxy vitamin D. Serum PTH, calcium & ALP (alkaline phosphatase) levels are normal. Normal s.calcium along with elevated serum phosphate exceeds concentration product of 75.

  • Treatment is surgical excision or phosphate binders.

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