Tumor CalcinosisPeriarticular extra capsular soft tissue masses of hyroxyapatite or amorphous calcium phosphate complex around major joints most often shoulder, hip & ankle is seen in tumor calcinosis. Disease usually appears in childhood & grows life-long.
The primary defect is hyper phosphatemia resulting from increase reabsorption of filtered phosphate by renal tubules. The most common findings are hyper phosphatemia, & elevated 1,25- dihydroxy vitamin D. Serum PTH, calcium & ALP (alkaline phosphatase) levels are normal. Normal s.calcium along with elevated serum phosphate exceeds concentration product of 75.
- Treatment is surgical excision or phosphate binders.