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Medicine

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Hematology

Question
9 out of 16
 

Auto immune destruction of platelets is seen in



A SLE
B Chronic Lymphocytic leukemia

C HIV
D All the above

Ans. D

All the above

Cause of Autoimmune Thrombocytopenia

1. Idiopathic - ITP

2. B. Secondary

a· SLE b· Lymphoma, CLL c· HIV d· Drugs e· Solid tumors

Extra Edge: (Harrison, 18th Pg.-968)

Laboratory testing is performed to evaluate for secondary causes of ITP and should include testing for HIV infection and hepatitis C (and other infections if indicated); serologic testing for SLE, serum protein electrophoresis, and immunoglobulin levels to potentially detect hypogammaglobulinemia; selective testing for IgA deficiency or monoclonal gammopathies and, if anemia is present, direct antiglobulin testing (Coombs test) to rule out combined autoimmune hemolytic anemia with ITP (Evans syndrome).

Hematology Flashcard List

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