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Orthopaedic

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Bone Tumor

Question
64 out of 104
 

Background lesions simulating bone tumors are all except



A Fibrous dysplasia
B Bone Island

C Hurler’s syndrome
D Bone infarct

Ans. C

Hurler’s syndrome

Fibrous dysplasia

a. These lesions are tumor-like growths that consist of replacement of the medullary bone with fibrous tissue, causing the expansion and weakening of the areas of bone involved.

b. Especially when involving the skull or facial bones, the lesions can cause externally visible deformities. The skull is often, but not necessarily, affected, and any other bone(s) can be involved.

c. Many patients have lesions localized in only one bone (monostotic fibrous dysplasia), affecting 70-80%.

d. Others have them in many bones (polyostotic fibrous dysplasia).

e. In 3% of cases, people suffering from fibrous dysplasia also have endocrine diseases and skin pigmentation; the three together constitute McCune-Albright syndrome. These endocrine diseases include precocious (early) puberty, often occurring as early as 6 years old

An enostosis or bone island represents a focus of mature compact (cortical) bone within the cancellous bone (spongiosa). Thought by some to be a tumor-like condition and by others a hamartoma, this benign lesion is probably congenital or developmental in origin and reflects failure of resorption during endochondral ossification. A bone island can be virtually diagnosed based on its characteristic clinical and radiologic features. Typically asymptomatic, the lesion is usually an incidental finding, with a preference for the pelvis, femur, and other long bones, although it may be found anywhere in the skeleton, including the spine.

Enchondroma Most commonly seen in the phalanges, Asymptomatic but commonly fractures. Ollier’s Disease = Multiple enchondromas. Maffucci’s Syndrome = Multiple enchondromas with soft tissue haemangiomas. Contain calcified chondroid matrix. Differential diagnosis: bone infarct. This often occurs within femur or tibia and typically demonstrates patchy sclerosis with demineralization

Hence by exclusion answer is Hurler syndrome.

Bone Tumor Flashcard List

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