Barrett’s esophagus is:
|D||Cancer of the esophagus|
a. The specialized intestinal type epithelium found in the Barrett's mucosa is the only tissue predisposed to malignant degeneration.
b. The hallmark of intestinal metaplasia is the presence of intestinal goblet cells. There is a high prevalence of biopsy-demonstrated intestinal metaplasia at the cardia, on the gastric side of the squamocolumnar junction, in the absence of endoscopic evidence of a columnar-lined esophagus.
c. Evidence is accumulating that these patches of what appears to be Barrett's in the cardia have a similar malignant potential as the longer segments, and are precursors for carcinoma of the cardia.
d. The long-term relief of symptoms remains the primary reason for performing antireflux surgery in patients with BE. Healing of esophageal mucosal injury and the prevention of disease progression are important secondary goals.
e. They should be considered for antireflux surgery when patient data suggest severe disease or predict the need for long-term medical management. Most patients with BE are symptomatic.