Best investigation to diagnose Riedel thyroiditis is? (DNB Dec 2010)
1). Middle-aged women.
2). Insidious, painless goiter
3). Local symptoms due to compression of the esophagus, trachea, neck veins, or recurrent laryngeal nerves.
4). Dense fibrosis disrupts normal gland architecture and can extend outside the thyroid capsule.
5). Despite these extensive histologic changes, thyroid dysfunction is uncommon.
6). The goiter is hard, non-tender, often asymmetric, fixed, leading to suspicious of a malignancy.
7). Diagnosis requires open biopsy as FNA biopsy is usually inadequate.
8). Treatment is directed to surgical relief of compressive symptoms.
9). Tamoxifen may also be beneficial.