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Golden Points

 

  1. Many antidepressants are prodrugs:
  2. Trazadone---nefazodone
  3. Fluoxetine---norfluoxetine
  4. Loxapine---amoxapine
  5. Amitriptyline---nortriptyline
  6. Imipramine---desirpramine
  7. Nefazodone is shortest acting, potent enzyme inhibitor
  8. Fluoxamine is also an enzyme inhibitor
  9. Fluoxetine is longest acting (half life 7-10 days)
  10. Citalopram is not an enzyme inhibitor




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