Coupon Accepted Successfully!



  1. Irinotecan
    1. Given IV infusion
    2. Used in refractory colorectal Ca
    3. Given in a prodrug form ,its active metabolite is SN38 which has cholinergic activity and hence results in diarrhea as its side effect which is different from dose related diarrohoea seen with other anticancer drugs.
    4. Anticholinesterase action Diarrhea occurs
  2. Toptecan
    a. Leukemia/lymphoma/ovarian/testicular Ca  
Extra edge
 → Both Inhibit Topoisomerase I

Test Your Skills Now!
Take a Quiz now
Reviewer Name