Purines, Pyrimidines and Nucleic Acid Metabolism
Carbamoyl phosphate is involved in the synthesis of:
|A||Purine and uric acid|
|B||Purine and pyrimidine|
|C||Purine and urea|
|D||Pyrimidine and urea|
Carbamoyl phosphate is synthesized in:
a. Mitochondrial matrix by carbamoyl phosphate synthetase I for urea synthesis.
b. Cytosol by carbamoyl phosphate synthetase II for pyrimidine synthesis.
The carbon of urea and pyrimidine is derived from carbamoyl phosphate.