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Medicine

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Respiratory

Question
6 out of 11
 

Carbon monoxide diffusion capacity decreases in all, except: (DNB Dec 2010)



A Emphysema

B Primary pulmonary hypertension

C Alveolar hemorrhage

D Infiltrative lung disease

Ans. C

Alveolar hemorrhage

Single Breath DLCO Study for Diffusion Capacity

1). In interstitial lung diseases the transfer capacity of the lungs is reduced. The diffusing capacity of lung for carbon monoxide (DLCO) is reduced in all patients with intrinsic lung disorders.

2). In obstructive lung diseases the transfer capacity of the lung is not affected.

3). The DLCO is not affected in patients with. Extraparenchymal restrictive lung diseases i.e. the restrictive lung diseases caused due to chest wall or muscular disorders.

4). A normal DLCO value in restrictive diseases excludes intrinsic lung disease and indicates extrinsic lung disorders due to chest wall pleura or neuromuscular lung disease.

5). The DLCO is the most sensitive parameter and findings may be abnormal even when the lung volumes are preserved.

Decrease value of DLCO is seen in­

1). Emphysema

2). Interstitial lung disease

3). Recurrent pulmonary emboli

4). Anemia

5). Severe CHF

6). Pulmonary artery hypertension

Increased level of DLCO is seen in­

1). Mild CHF (Due to pulmonary flow) (Note - It is increase in mild CHF and reduce in Severe CHF)

2). Alveolar hemorrhage

3). Polycythemia

4). Left to right shunts

5). In Goodpasture’s syndrome alveolar hemorrhage occurs therefore (DLCO) is increased.

Respiratory Flashcard List

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