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Pathology

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CVS

Question
14 out of 17
 

Cardiac involvement in carcinoid syndrome is characterized, by: (AIIMS Nov 2013)



A Calcification tricuspid valve

B Intimal fibrosis of right ventricle, tricuspid and pulmonary valve.

C Involvement of the major blood vessels is commonly seen

D Equal involvement of both the sides of the heart

Ans. B Intimal fibrosis of right ventricle, tricuspid and pulmonary valve

' Cardiac lesions are present in 50% of the patients with the carcinoid syndrome.

' These are largely right-sided due to inactivation of both serotonin and bradykinin in the blood during passage through the lungs by the monoamine oxidase present in the pulmonary vascular endothelium.

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