Cardiac involvement in carcinoid syndrome is characterized, by: (AIIMS Nov 2013)
|A||Calcification tricuspid valve|
|B||Intimal fibrosis of right ventricle, tricuspid and pulmonary valve.|
|C||Involvement of the major blood vessels is commonly seen|
|D||Equal involvement of both the sides of the heart|
• ' Cardiac lesions are present in 50% of the patients with the carcinoid syndrome.
• ' These are largely right-sided due to inactivation of both serotonin and bradykinin in the blood during passage through the lungs by the monoamine oxidase present in the pulmonary vascular endothelium.