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Myxoma (Ref. Hari. 18th ed., pg -1979)

Cardiac myxoma

  1. Benign Q cardiac tumour. It is the most common benign tumour of heart.
  2. Most common tumour of heart is myxoma
  3. Commonest site of myxoma is left atrium.
  4. Usually sporadic Q, may be familial Q (autosomal-dominant) Q. (May 2007)
  5. It may mimic infective endocarditis (fever, weight loss, clubbing, raised ESR), or mitral stenosis Q (left atrial obstruction, systemic emboli, Af).
  6. A 'tumour plop' may be heard, and signs may changed according to posture.
  7. Gradient in pulmonary artery wedge pressure and left ventricular end diastolic pressure is seen in Left atrial myxoma.
  8. Distance metastasis does not occur.
  9. Tests: Echocardiography.            
  10. Treatment: Excision. Recurrence can occur specially in familial type – Harrison, 18th edition, page 1980) 

Important Points:


Familial variety:


  1. Carney complex :
    1. Myxoma          
    2. Lentigenes or pigmented neavei    
    3. Endocrine over activity (adrenal or pituitary)
  2. NAME syndrome :
    1. Nevi                                        
    2. Atrial myxoma
    3. Myxoid neurofibroma                        
    4. Ephilides
  3. LAMB syndrome:
    1. Lentigenes        
    2. Atrial myxoma      
    3. Blue nevi  

(Important Points: Most common tumour metastasizing to heart is malignant melanoma)

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