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Physiology

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Blood

Question
16 out of 42
 

Cell type, which lacks HLA antigen, is: (DNB Dec. – 2008)



A Monocyte
B Thrombocytes

C Neutrophil
D Red blood cell

Ans. D Red blood cell
  1. Antigen presenting cells include specialized cells called dendritic cells in the lymph nodes and spleen and the Langerhans dendritic cells in the skin Macrophages and B cells themselves can also function as antigen presenting cells.
  2. In antigen-presenting cells, polypeptide products of antigen digestion are coupled to protein products of the major histocompatibility (H LA) complex genes and presented on the surface of the cells.
  3. The products of the MHC genes are called human leukocyte antigens (HLA) The genes of the HLA are located on the short arm of chromosome 6 Q, encode glycoproteins and are divided in two classes based on their distribution and function.
  4. The class I antigens are found on all ‘nucleated’ cells while the class II antigens are present in antigen-presenting cells including B cells and activated T cells. Q

Blood Flashcard List

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