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Pathology

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Inflammation

Question
4 out of 13
 

Chemotaxis in response to activation of cells results in- (AIPG 2012)



A Random multidirectional movement

B Unidirectional motion

C Adhesion to endothelium

D Augmented oxygen dependent bactericidal effect

E Phagocytosis

Ans. B Unidirectional motion

Chemotaxis

· After extravasation from the blood vessels, leukocytes emigrate in tissues towards the site of injury by chemotaxis.

· Chemotaxis is unidirectional locomotion oriented along a chemical gradient

· This chemical gradient is created by the substance called chemoattractants (chemotactic agents), which may be:-

1. Exogenous Bacterial products

2. Endogenous C5a, LTB4, IL-1, TNF, IL-8

Note: C5a is the most powerful chemoattractant.

Inflammation Flashcard List

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