Chief Cells are found in (AIPG – 2009)
References: 1. Pg. 1152, 53; Gray's Anatomy (39th Ed.), 2. Pg. 1855; Harrison’s Internal medicine (18th Ed.)
1. Chief cells are usually basal (fundal-a) in position.
a. Chief (Peptic) cells are the source of digestive enzymes like pepsin and lipase.
b. These cells are cuboidal with round nucleus and contain lots of zymogen granules.
2. Parietal /Oxyntic cells produce hydrochloric acid and the intrinsic factor.
a. These cells are oval with centrally placed nucleus.
b. They are mainly located in the apical half of the body (d) of gland, reaching as far as the neck (c).
3. The microstructure of the gastric mucosa in surface to depth sequence is:
a. Gastric pit (foveolus) b. Isthmus (neck)
c. Body (gastric gland) d. Base (fundus).
4. Surface mucus cells are distributed in the gastric pit - (b) region of the gastric mucosa.
5. Mucus neck cells are abundant in the neck region as the name is also suggesting.
6. Neuroendocrine cells are situated mainly in the deeper /basal parts of the glands, along with the chief cells.