|A||Buffered alkaline solution of glutaraldehyde|
|B||Solution of iodine in ethyl alcohol|
|C||50% solution of isopropyl alcohol|
|D||Quarternary ammonium compound|
a. Glutaraldehyde 2% ( CIDEX) is a high-level disinfectant that has been used extensively in flexible endoscopy. Before disinfection, scopes should receive a thorough manual cleaning to eliminate gross debris. To achieve high-level disinfection, the internal and external surfaces and channels should come into contact with the disinfecting agent for a minimum of 20 minutes.
b. Glutaraldehyde has certain disadvantages. These are:
i. It requires activation before use;
ii. It is irritating to the skin, eyes, and nasal mucosa,
iii. Its use requires special ventilation or a ducted fume hood.
c. An alternative to glutaraldehyde is orthophthaldehyde (OPA., a newer agent approved by the Food and Drug Administration (FDA. for high-level disinfection. OPA is odorless and nonirritating and does not require activation before use.
d. Noncritical items are those that come in contact with intact skin (e.g., blood pressure cuffs). They require only washing or scrubbing with a detergent and warm water or disinfection with an intermediate-level or low-level germicide for 10 minutes.