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Medicine

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Kidney

Question
11 out of 20
 

Clinical features of minimal change. Glomerulo-nephritis are all except



A Hypertension
B Edema

C Selective proteinuria
D Fever

Ans. A Hypertension

Primary Glomerular diseases causing nephrotic syndrome (Ref. H-18th Edi, P- 2345)

A. Minimal Change Disease

i. This occurs commonly in children.

ii. The blood pressure is normal.

iii. GFR is normal or slightly reduced. No significant urinary sediment is seen.

iv. Proteinuria in the nephrotic range is present.

v. Selective proteinuria is seen (there is selective excretion of low molecular weight protein like albumin and absence of high molecular weight protein like globulin in the urine).

vi. Selective presence of low molecular weight protein in urine indicates a good prognosis.

Microscopy

Investigation

Observation

Light microscopy

No abnormality

Electron microscopy

Fusion of foot processes

Immunofluorescence

Absence of immunoglobulin or complement

Kidney Flashcard List

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