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Prolapse, Urogynecology & Infections

Question
19 out of 30
 

Clomiphene citrate is indicated in (LQ)



A Stein-Leventhal syndrome

B Endometriosis

C Asherman’s syndrome

D Carcinoma endometrium

Ans. A
Stein-Leventhal syndrome

If the patient wishes to become pregnant, clomiphene or other drugs can be employed for induction of ovulation for female infertility

a. Clomiphene - can sometimes stimulate a man's own pituitary gonadotropins (when his pituitary is intact) there by increasing testosterone and sperm production for male infertility

b. Clomiphene citrate is non-steroidal estrogen antagonist it induces ouulation in 60% of women with stein-Leventhal syndrome (PCOS) and is the initial treatment of choice. Adverse effects - Poly cystic ovaries, multiple pregnancy hot flushes, gastric upset, vertigo, allergic dermatitis, risk of ovarian tumor may be increased

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