CNS Part- 2
Compared to the other antidepressant drugs mirtazapine has the distinct ability to act as an antagonist of (LQ)
|C||Alpha 2 receptors|
Mirtazapine blocks presynaptic α2 receptors on NA and 5-HT neurons. This increases the release of both NA and 5-HT. It also inhibits 5-HT2 and 5-HT3 receptors.