Male Genital Tract
Condyloma are mostly caused by HPV types: (LQ)
|A||11 and 13|
|B||6 and 11|
|C||6 and 13|
|D||30 and 33|
a. Condyloma are most commonly caused by HPV types 6 and 11.
b. Condyloma acuminatum is a benign tumor caused by human papilloma virus (HPV).
c. It is related to the common wart (verruca vulgaris) and may occur on any moist mucocutaneous surface of the external genitalia in either sex.
d. Also, HPV and associated diseases are sexually transmitted.
e. On the penis, these lesions occur most often about the coronal sulcus and inner surface of the Prepuce.
f. They consist of single or multiple sessile or pedunculated, red papillary excrescences that vary from 1 mm to several mm in diameter.
g. Histologically a branching, villous, papillary connective tissue stroma is covered by a thickened hyperplastic
h. Epithelium that may have considerable superficial hyperkeratosis and thickening of the underlying epidermis (acanthosis).
i. The normal orderly maturation of the epithelial cells is preserved.
ii. Clear vacuolization of the prickle cells (Koilocytosis), characteristic of HPV infection is noted in these lesion.
iii. The basement membrane is intact, and there is no evidence of invasion of the underlying stroma.
iv. Condyloma acuminata tend to recur but do not evolve into invasive cancers.