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Medicine

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Endocrine

Question
19 out of 20
 

Confirmatory investigation for Acromegaly is: (LQ)



A Insulin induced GH suppression

B Glucose induced GH suppression

C Random GH assay

D IGF - I level

Ans. B

Glucose induced GH suppression

Test

1). Increase heal pad thickness seen on X-ray lateral view of the heal

Most common cause of increase heal pad thickness is heal injury (AIIMS Nov 2010).

2). Elevated IGF-I. Usually > 5 times normal.

3). Serum GH not suppressed following oral glucose. OGTT test (75 gms of glucose given. After 1 hour if GH>1 ng/ml- suggestive of GH tumor.) It is the most definite test.

4). Confirmation- MRI/CT neoplasm

Endocrine Flashcard List

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