Second Trimester Mtp (13-20 Weeks)
- Misoprostol (PGE1) tablet vaginally is most widely used for second trimester pregnancy termination.
- Ethacridine lactate extra-amniotically can also be used for second trimester pregnancy termination. A solution of 10 mL of 0.1 % ethacridine is used for each gestational week, up to a maximum 150 mL. Induction abortion interval is about 30 h, even with intravenous oxytocin as an augmenting agent.
NOTE: Intra-amniotic saline/mannitol/urea, etc. are no longer used because of risk of maternal mortality.