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Physiology

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Nerve Muscle Physiology

Question
8 out of 19
 

Contraction of covering binding sites on actin is prevented by:(DNB Pattern)



A Tropomyosin
B Troponin

C Calmodulin
D Thypmosin

Ans. B Troponin

a. In resting muscle fibers Troponin I is tightly bound to Actin while Tropomyosin covers the site where myosin heads bind the Actin Q.

b. Therefore troponin-tropomyosin complex forms a relaxing protein which prevents interaction between Actin and Myosin in resting muscles.

c. When Calcium ions are released by action potential they bind to Troponin C.

d. This process weakens the binding of Troponin I with Actin and cause lateral movement of Tropomyosin.

e. This process uncovers the binding sites of Actin and myosin heads leading to contraction.

Nerve Muscle Physiology Flashcard List

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