Correct pair of Ig subclass with their heavy chain:
|A||IgM - α|
|B||IgG - γ|
|C||IgM - δ|
|D||IgE - γ|
In human,s genes for light chains-kappa (k) is in chromosome 2; for light chain lambda (λ) is in chromosome 22 and genes for heavy chains are in chromosome 14.
Each of the 5 classes of immunoglobulin has a characterstic type of heavy chain – alpha (α) in IgA, gamma (γ) in IgG, delta (δ) in IgD, mu (μ) in IgM and epsilon (ε) in IgE.
Immunoglobin has 2 identical light (L) & 2 identical heavy (H) chains, each containing variable (V) & constant (C) regions. Variable regions of light-& heavy chains (i.e. VL & VH) bind to specifc antigen and form a part of Fab (antigen binding fragment).