Gram Positive Bacilli
Corynebacterium diphtheriae toxin acts by
|A||Inhibition of protein synthesis|
|B||Competitive inhibition of cytochrome|
|C||Killing susceptible cells|
|D||All of the above|
a. Diphtheria toxin is an protein having two components A and B having a molecular weight of 24,000 and 38,000 Da respectively.
b. Diphtheria toxin acts by inhibiting elongation factor 2, which is required for protein synthesis.
c. Inhibition of protein synthesis disrupts normal cellular physiologic functions.
d. All cells of the body are susceptible to its action except RBC’s.
e. It has a special affinity for myocardium, nerve endings and adrenals.