55 out of 100
Cyclosporine is active against lymphocytes: (LQ)
Ans. A T Lymphocyte
- CYCLOSPORINE acts by inhibition of production and release of interleukin-2 which leads to inhibition of T lymphocyte proliferation. It is nephrotoxic and hepatotoxic.
- Hirsutism, seizure and gum hyperplasia are other side effects.
- It is most effective drug to prevent rejection of transplanted organ.
- Tacrolimus, sirolimus and everolimus are similar drugs with identical mechanism of action.