Cystosarcoma phylloides in a:
|A||Sarcoma of the urinary bladder|
|B||Cystic ovarian tumour|
|D||Sarcoma of the gall bladder|
(REF. SABISTON SURGERY 18TH EDN PG 1323)
b. Intermediate neoplastic growths comprising phyllodes tumors, which contain a biphasic proliferation of stroma and mammary epithelium. With increasing cellularity, an invasive margin, and truly sarcomatous appearance, these tumors may be classified as malignant phyllodes tumors.
c. Benign phyllodes tumors are recognized as firm, lobulated masses between 2 and up to 40 cm in size, with an average size of about 5 cm (larger than average fibroadenomas).
d. Histologically, these tumors are similar to fibroadenomas, but the whorled stroma forms larger clefts lined by epithelium that resemble clusters of leaflike structures. The stroma is more cellular than a fibroadenoma, but the fibroblastic cells are bland and mitoses are infrequent.