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Physiology

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Respiration

Question
10 out of 16
 

Decreased O2 affinity of Hb in blood with decreased pH:(LQ)



A Haldane effect
B Double Haldane effect

C Bohr effect
D Double Bhor effect

Ans. C Bohr effect

I. Bohr effect: ­

a. Definitionthe decrease in O2 affinity of Hb when the pH of the blood falls is called the Bohr effect Q

b. DeoxyHb binds H+ more actively than does oxy Hb.

c. PH of blood falls as its CO2 content increases so that when the PCO2rises the curve shifts to the right and the P50 rises this is Bohr effect.

II. Haldone effect: CO2 transport in blood:

a. Definitionthe ability of deoxygenated - blood to carry more CO2 than oxygenated Hb. Q

b. Deoxygenated Hb (weak acid) binds more H+ than oxy Hb (stronger acid) does and forms carbamino compound (Hb-CO2).

c. Venous blood carries more CO2 than Arterial blood and CO2 uptake is facillated in tissues and CO2 release is facilitated in the lungs.

d. Thus the Haldane effect aproximately doubles the amount of CO2 released from the blood in the lungs and approximately doubles the pickup of CO2 in the tissues Q.

Respiration Flashcard List

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