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Medicine

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Endocrine

Question
18 out of 28
 

Detemir is a? (PNQ)



A Sulphonylurea
B Insulin

C Thioglitazone
D Alpha glucosidase inhibitor

Ans. B

Insulin

Pharmacology of Insulin (Ref. Hari-18th ed. Pg- 2993, table 344.10)

Preparation

1). Ultra Short-acting =

a. Aspart

b. Glulisine

c. Lispro

2). Short acting = Regular

3). Intermediate acting =

a. NPH

b. Lente

4). Long acting =

a. Detemir

b. Glargine

Recent Advances (New drugs)

DEGLUDEC


Insulin degludec is an ultralong-acting basal insulin analogue. It is administered via subcutaneous injection. It can be given daily or up to three-times a week to help control the blood sugar level of those with diabetes. It has duration of action that lasts up to 40 hours.

IMEGLIMIN

Imeglimin is an oral anti-diabetic. It is an oxidative phosphorylation blocker that acts to inhibit hepatic gluconeogenesis, increase muscle glucose uptake, and restore normal insulin secretion.

Drugs which can be used in both type I and type II diabetes (LQ 2012)

1). Acarbose

2). Pramlintide

3). Insulin

Endocrine Flashcard List

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