Drugs inhibiting the formation of IL-2 are (PGI Nov 2011)
· Cyclosporine and tacrolimus inhibits antigen stimulated activation and proliferation of helper cells as well as expression of IL-2.
· Cycloserine is an antitubercular drug that acts by inhibiting bacterial cell wall synthesis
· OKT3 - is monoclonal antibody. It activates T cells non specifically and releases cytokines, specially TNF-alpha