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Pharmacology

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GIT

Question
30 out of 53
 

Drugs used for H. Pylori include the following EXCEPT:



A Bismuth
B Amoxicillin

C Mosapride
D Clarithromycin

Ans. C Mosapride

H. pylori is a bacteria that is difficult to eradicate. Symptomatic patients may require multiple courses of antibiotic and bismuth regimens to eradicate it completely.

The most successful are the Triple and Quadruple multi-drug regimens:

Name

Drug 1

Drug 2

Drug 3

Drug 4

OCA

Omeprazole (20 mg BD.

Clarithromycin (500 mg BD.

Amoxicillin (1g BD.

-

OCM

Omeprazole (20 mg BD.

Clarithromycin (500 mg BD.

Metronidazole (500 mg BD.

-

OBTM

Omeprazole (20 mg BD.

Bismuth Subsalicylate(2 tabs ID.

Tetracycline (500 mg ID.

Metronidazole

Cisapride, mosapride, andrenzapride are selective 5-HT4 agonists. They mediate intestinal secretion, augmentation of peristalsis. Renzapride is a selective 5-HT 4 agonist. They are not used to treat H. pylori infection.

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