Growth Hormone Deficiency
Growth impairment starts within a few months after birth.
Height is usually < 3rd percentile.
Height velocity ts often as low as 1 cm /year
C/F. Short with normal body proportionQ. Bone age may be delayed, Height age is less than the skeletal age and chronological ageQ. Facial appearance is "doll like".Q New born with congenital GHD may present with severe hypoglycemia & ACTH deficiency. Q
- Peak GH levels less tr.3n 10 my/ml during provocative stimulation teats. Insulin, arginine, glucagon, L-dopa and clonidine.
- Small sella turcica on x-ray skull / CT / MRI.