Sterilization and disinfection
Endotoxic shock is initiated by (AIIMS May 2009)
|C||Increased vascular permeability|
a. The receptor for the endotoxin in humans is the TLR-4 located on the surface of antigen presenting cells.
b. Binding to the receptor activates a cascade of enzymatic reactions which finally leads to the activation of the genes for the proinflammatory cytokines.