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Medicine

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Endocrine

Question
31 out of 33
 

Epalrestat is a (PNQ)



A Lipid lowering agent
B Anti-hypertensive drug

C Anti-diabetic drug
D None of the above

Ans. D

None of the above

(It does not reduce the blood sugar but it prevents the onset of diabetic complication).

Pathophysiology of diabetic complication.

1). In diabetes glucose is converted into sorbitol which is a tissue toxin. Q

2). Enzyme required in this step is aldose reductase. Q

3). Recently a new drug Epalrestat (PNQ) Qhas been launched which is a aldose reductase inhibitor. (PNQ)

Which is supposed to reduce the complication of diabetes.

Recent Advances: Epalrestat is a aldose reductase inhibitor (PNQ) Epalrestat is a recently launched drug in Indian Market. Its name is not there in Hari 18th ed. also !!!..

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