Loading....
Coupon Accepted Successfully!

Dermatology

Open Flashcards

Vasculitis

Question
2 out of 11
 

Erythema nodosum can seen in following except? (LQ)



A Acute pancreatitis
B TB

C SLE
D Pregnancy

Ans. A
(Acute pancreatitis)

Erythema Nodosum:
Clinical Features:

1). Symmetric, tender, erythematous, warm nodules and raised plaques on the anterior aspects of the lower extremities

2). Acute onset

3). No ulceration

4). More common in women than in men

Histopathology:

1). Mostly septal panniculitis without vasculitis

2). Thickened septa with inflammatory cells

3). Neutrophils in early lesions and histiocytes and Miescher granulomas in late-stage lesions

4). Treatment of the associated disorder.

Etiology:

1). Idiopathic

2). Medical causes, excluding infections

a. Sarcoidosis and other granulomatous disease (granulomatous mastitis)

b. Inflammatory bowel disease and

c. Diverticulitis

d. Rheumatological and autoimmune diseases, including lupus erythematosus, Reiter’s syndrome, Sjögren’s syndrome, Beh|et’s disease, coeliac disease, autoimmune Hepatitis.

e. Malignancy (uncommon, mainly haematological but others are recorded including lung, pancreas, renal, stomach, colon, uterus, cervix and others)

f. Haematological stem cell transplantation

g. Pregnancy

h. Acne fulminans (sometimes with isotretinoin)

3). Infections

a. Bacterial:

i. Group A â-haemolytic Streptococcus uncommonly Group C streptococci

ii. Other bacterial upper respiratory infections, e.g. Moraxella , meningococcus

iii. Staphylococcus aureus (uncommon); also breast abscesses, probably

iv. staphylococcal

v. Tuberculosis (uncommon but over 10% in some geographical areas)

vi. Leprosy; erythema nodosum leprosum may be chronic

vii. Atypical mycobacterial infection

viii. Yersinia (up to 15% in children)

ix. Gastrointestinal infections: Salmonella, Shigella, Klebsiella

x. Campylobacter

xi. Escherichia coli

xii. Brucellosis

xiii. Cat scratch fever

xiv. Borrelia burgdorferi

xv. Mycoplasma

xvi. Genitourinary: syphilis, gonorrhoea, lymphogranuloma venereum, chancroid

xvii. Others: Q fever, tularaemia, Pasteurella pseudotuberculosis, leptospirosis,

xviii. rickettsiae

b. Other infections:

i. Unspecified upper respiratory infections

ii. Chlamydia (including psittacosis)

iii. Coccidioidomycosis

iv. Histoplasmosis

v. Blastomycosis

vi. Dermatophytes

vii. Hepatitis B and C

viii. Parvovirus B19

ix. Cytomegalovirus

x. Toxoplasmosis

xi. Visceral larva migrans

xii. Others: amoebiasis/giardiasis (both in the same individual), herpes simplex,

xiii. varicella-zoster, HIV, infectious mononucleosis, measles, aspergillosis,

xiv. trichomonas, ascariasis

4). Medications

a. Sulphonamides, penicillins

b. Halides

c. Oral contraceptive pill

d. Hepatitis B vaccine

e. Isotretinoin

f. Imatinib mesylate

Treatment:

1). Treatment of the associated disorder.

2). Bed rest, aspirin, nonsteroidal antiinflammatory drugs.

3). Systemic corticosteroids are rarely indicated.

Vasculitis Flashcard List

11 flashcards
1)
2)
3)
4)
5)
6)
7)
8)
9)
10)
11)