Gram Negative Bacilli
Escherichia coli can be classified by their characteristic virulence properties and different mechanisms that cause disease. To which group does the verotoxin producing E. coli 0157:H7 serotype belong? (AIPG 2009)
|A||Enteroaggregative E. coli (EAEC)|
|B||Enterohemorrhagic E. coli (EHEC)|
|C||Enteroinvasive E. coli (EIEC)|
All of the above classes of E. coli cause diarrhea. However, only EHEC produce a verotoxin that has many properties that are similar to Shiga toxin.
EHEC has been associated with hemorrhagic colitis, a severe form of diarrhea, and with hemolytic uremic syndrome (HUS). HUS is a disease resulting in acute renal failure, microangiopathic hemolytic anemia, and thrombocytopenia.