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Medicine

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Endocrine

Question
2 out of 11
 

Extra adrenal Pheochromocytoma predominantly secretes: (LQ)



A Epinephrine
B Norepinephrine

C Dopamine
D DOPA

Ans. B

Norepinephrine

Adrenal Medulla

1). Normally adrenal medulla secretes 80% epinephrine and 20% norepinephrine.

2). In adrenal pheochromocytoma mainly epinephrine is secreted, in extra adrenal norepinephrine is secreted exclusively.

3). Malignant pheochromocytoma secretes epinephrine, norepinephrine and dopamine.

4). Pheochromocytomas roughly follow the 10% rule: 10% are malignant, 10% are extra-adrenal, 10% are bilateral, and 10% are familial.

Associations -90% are sporadic. 10% are part of a hereditary cancer syndrome eg MEN2a and 2b, neurofibromatosis, von Hippel-Lindau syndrome.

Note: Pheochromocytomas is a highly vascular tumor that is why FNAC is not done in this case. (LQ)

FNAC is also not done in case of thymomas (It is inconclusive)

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