False about Latanoprost: (AIIMS Nov 2014)
|A||is a prostaglandin F2a analogue|
|B||decreases intraocular pressure by decreasing aqueous production|
|C||has a short half-life in the plasma making systemic side-effects uncommon|
|D||is associated with conjunctival hyperaemia|
It decreases intraocular pressure by increasing uveoscleral outflow. it has a half-life of 17 minutes in the plasma and therefore systemic side-effects are uncommon.It increases iris pigmentation by increasing the melanin production. The number of melanocytes is not altered.