Fluoxetine is a: (DNB June 2011)
|A||Noradrenaline uptake inhibitor|
|B||Serotonin uptake enhancer|
|C||Serotonin uptake inhibitor|
Fluoxetine is a potent and selective inhibitor of serotonin (5-HT) uptake, but not of norepinephrine uptake, in the central nervous system (CNS). Because uptake inactivates serotonin by removing it from the synaptic cleft, uptake inhibition by fluoxetine enhances serotonergic function.