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Medicine

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Rheumatology

Question
7 out of 10
 

Focus score is use in the diagnosis of which of the following condition? (PNQ)



A SLE
B Marfan syndrome

C Sjögren’s syndrome
D RA

Ans. C Sjögren’s syndrome (SS)

Recent Advances: Focus Score

The verification of SS should consider all three components of diagnostic relevance:

a. Focal sialadenitis, b. Keratoconjunctivitis sicca c. Associated disease.

Focus score (the number of mononuclear cell infiltrates containing at least 50 inflammatory cells in a 4 mm2 glandular section) of greater than 1 is probably the single most important test result in the diagnosis of the oral component in SS.

Treatment Of Scloroderma

Treatment is aimed at symptomatic relief.

1. Pilocarpine given orally appears to improve sicca manifestations.

2. Hydroxychloroquine is helpful for arthralgias.

3. Glucocorticoids or other immunosuppressive agents (i.e, cyclophosphamide) are indicated for the treatment of extraglandular manifestations.

Rheumatology Flashcard List

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