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Dermatology

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STD

Question
10 out of 42
 

For lymphogranuloma venereum the drug of choice is: (AIIMS Nov 2013)



A Ceftriaxone

B Erythromycin

C Doxycycline

D Ampicillin

Ans. C
Doxycycline

1. Lymphogranuloma venereum is a STD caused by Chlamydia trachomatis strains of the L1' L2, and L3 serovars.

2. A primary genital lesion develops from 3 days to 3 weeks after exposure which is a small, painless vesicle or non-indurated ulcer (noticed rarely) or papule located on the penis in males and on the labia, posterior vagina, or fourchette in females. The primary lesion is noticed by less than 33% of men with LGV and only rarely by women. Ulcer is usually transient and self-healing’.

3. Most common presenting picture in heterosexual men is the inguinal syndrome, which is characterized by painful inguinal lymphadenopathy (bilateral in 1/3) starting 2 to 6 weeks after presumed exposure. These enlarged glands are called bubos. Extensive involvement of chains of inguinal nodes above and below the inguinal ligament (the groove sign of greenblat) is common.

4. Diagnosis is confirmed by Complement Fixation Test – value > 1:64 is considered significant.

5. Treatment of choice is Doxycycline.

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