- Potent analgesic
- S/E Nausea & Vomiting
- Soda lime produces toxic product Dichloroacetylene which cause Nerve Palsies. & produces phosgene.
- Most common nerve involved with Trilene, 5th All except 1, 9 & 11 may be involve.
- XENON- is inert, Colourless and odourless gas with no irritation to the respiratory tract. Well tolerated with gas induction
- Low blood/gas and oil/water partition co-efficient allowing rapid induction and eduction (AIIMS Nov 06)
- Produces unconsciousness with analgesia and a degree of muscle relaxation
- MAC of 60-70% allows a reasonable inspired oxygen concentration
- It does cause respiratory depression, to the point of apnea.
- It is cardiac stable.
- Not metabolized in the body and is eliminated rapidly and completely via the lungs.
- It is non toxic and is not associated with allergic reactions
- Stable in storage, no interaction with anaesthesia circuits or soda lime. Should not be used with rubber anaesthesia circuits as there is a high loss through the rubber
- Non flammable. (AIIMS Nov 06)
- Expensive - Routine usage will only be possible with a closed circuit delivery system that recycles xenon.
- Owing to environmental concerns there may be no alternative but to use xenon even if it incurs an increase in cost.