Coagulase Negative Staphylococci (CNS)
- Part of the normal flora of the skin.
- About 33 species are recognized, S. epidermidis accounts for 75% of clinical isolates.
- CNS are opportunistic pathogens causing infections in debilitated or immunocompromised patients and patients fitted with implants & prosthetic devices.
- Morphologically similar to S. aureus & method of isolation are the same
- They can be distinguished from S. aureus by failure to coagulate plasma and by lack of clumping factor & deoxyribonuclease.
- Staphylococcus epidermidis:
- Staphylococcus saprophyticus: Important cause of acute urinary tract infection in young healthy sexually active women.