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Non-Healing Midline Granuloma

  1. Destructive disease of nose and midface
  2. No lung/kidney involvement
  3. Is a malignant lymphoma
  4. Diagnosis : many repeated biopsies may be needed to diagnose
  5. Treatment: radiotherapy, followed by debridement and nasal prosthesis
  6. Steroids and cytotoxics contraindicated since they reduce the immune response

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