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Wegener’s Granulomatosis

  1. Systemic disorder                                                              
  2. Unknown etiology
  3. Upper and lower airway involvement                              
  4. Skin and kidney involvement
  5. Clear/blood stained nasal discharge -> purulent          
  6. Crusting, granulations
  7. Septal perforation/saddle nose                                      
  8. May involve mid-face
  9. Cavitary (single/multiple) lesions of C-Xray                    
  10. Cause of death: renal failure
  11. Diagnosis: biopsy                                                        
  12. Treatment: steroids, cytotoxics

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