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Acute Leukemia

CD markers of various cells
  1. Stem cells = CD 34
  2. Both meyloid and lymphoid series cells = CD 45.
  3. Pan B cells marker = CD 19
  4. Pan T cells marker = CD 3
  5. Monocytic cells = CD 14
  6. All granulocyte = CD 15
  7. Thrombocytes = CD 61
 
Important T cell Markers
Pan Tcell markers Subset markers
Markers that are common to all cells of a given type Pan T cell markers include
CD2
CD3
CD5
CD7
Markers that are present only on a subset of population of cells in a given lineage
Subset T cell markers include
CD4
CD8
CD Marker T cell
CD 45 RA
CD 45 RB
CD45 RC
CD45 RO
Subset T, medullary thymocytes “naïve” T cell
All leukocytes
Subset T, medullary thymocytes, “naïve” T cells
Subset T, cortical thymocytes, “memory” T cells
 
Leukemias
 
Leukemias are malignant neoplasms of the hematopoietic stem cells, arising in the bone marrow, that flood the circulating blood or other organs.




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