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Extra cellular defect

  1. Autoimmune
    1. Warm antibodies  
    2. ​Cold antibodies
  2. Fragmentation hemolysis
    1. DIC, TTP, HUS              
    2. Prosthetic heart valve          
    3. Bum thermal injury
  3. Hypersplenism
  4. Abeta lipo proteinemia
  5. Infection
    1. Malaria
    2. Kala azar
Extra Edge

Most of the cellular defects are inherited (paroxysmal nocturnal hemoglobinuria is acquired) and most of the extracellular defects are acquired (abeta lipoproteinemia is inherited)

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