- Oxygen transport depends on the maintenance of intra cellular hemoglobin in the reduced (Fe+2) and is now in capable to binding oxygen.
- Hereditary methemoglobinemia is due to either the presence of one of the M hemoglobins or to the deficiency of the enzyme cytochrome b5 reductase.
- Lf me, hemoglobin exceeds gm% (% of the total Hb) affected individual which have clinically obvious cyanosis.
- Methylene blue
- Ascorbic acid